:root {
  --page: #f8f7f2;
  --surface: #ffffff;
  --surface-soft: #eef5f3;
  --surface-warm: #fbfcfa;
  --ink: #1f2a27;
  --muted: #66736f;
  --line: #b8ccc6;
  --accent: #28706a;
  --accent-dark: #1f5955;
  --accent-soft: #e8f3f2;
  --accent-border: #9fc9c3;
  --warning: #6f470d;
  --warning-soft: #fff6de;
  --danger: #7f2620;
  --danger-soft: #fff2df;
  --stage: #314f55;
  --focus: #9c6b10;
  --shadow: 0 18px 42px rgba(35, 52, 48, 0.058);
  --shadow-soft: 0 9px 24px rgba(35, 52, 48, 0.04);
  --banner-end: #46676b;
  --banner-text: #f8fbfa;
  --eyebrow: #3f625d;
  --warning-border: rgba(111, 71, 13, 0.42);
  --warning-body: #000000;
  --tabs-border: #afc5be;
  --tabs-bg: rgba(255, 255, 255, 0.9);
  --tabs-shadow: rgba(35, 52, 48, 0.036);
  --tab-separator: rgba(111, 136, 130, 0.62);
  --tab-hover-border: #a8beb7;
  --tab-hover-bg: rgba(248, 252, 251, 0.98);
  --active-tab-inset: rgba(255, 255, 255, 0.8);
  --active-tab-shadow: rgba(40, 112, 106, 0.08);
  --control-hover-border: #9bbab2;
  --control-hover-bg: #f8fcfb;
  --note-bg: #eef7f5;
  --note-warning-text: #5e3a00;
  --button-text: #ffffff;
  --input-inset: rgba(255, 255, 255, 0.8);
  --button-shadow: rgba(40, 112, 106, 0.12);
  --button-hover-shadow: rgba(40, 112, 106, 0.15);
  --button-active-shadow: rgba(40, 112, 106, 0.09);
  --soft-shadow: rgba(31, 42, 39, 0.055);
  --secondary-shadow: rgba(31, 42, 39, 0.045);
  --secondary-hover-shadow: rgba(31, 42, 39, 0.06);
  --table-header-line: #9eb9b1;
  --table-stripe: rgba(241, 247, 245, 0.64);
  --footer-bg: rgba(255, 255, 255, 0.86);
  --logo-card-bg: #ffffff;
  --reference-border: #aeb7b4;
  --reference-bg: #fbfaf6;
  --reference-label-bg: #2f3433;
  --reference-label-text: #fffdf7;
  --reference-text: #252b29;
  --reference-hover-bg: #ece8dd;
  --reference-hover-text: #111615;
  --reference-separator: #c9cfcc;
  --reference-shadow: rgba(31, 42, 39, 0.12);
}

:root[data-theme="dark"] {
  color-scheme: dark;
  --page: #0d1110;
  --surface: #151b1a;
  --surface-soft: #1d2322;
  --surface-warm: #181f1e;
  --ink: #e3ded6;
  --muted: #b7ada3;
  --line: #4f625c;
  --accent: #78aaa3;
  --accent-dark: #b8d0ca;
  --accent-soft: #182825;
  --accent-border: #6f8d85;
  --warning: #bda67b;
  --warning-soft: #1a1815;
  --danger: #dfa29a;
  --danger-soft: #241b1a;
  --stage: #13282d;
  --focus: #d8a657;
  --shadow: 0 18px 42px rgba(0, 0, 0, 0.32);
  --shadow-soft: 0 9px 24px rgba(0, 0, 0, 0.24);
  --banner-end: #253f42;
  --banner-text: #f0f6f4;
  --eyebrow: #9fc0b9;
  --warning-border: rgba(189, 166, 123, 0.22);
  --warning-body: #cfc8bc;
  --tabs-border: #596d66;
  --tabs-bg: rgba(21, 27, 26, 0.94);
  --tabs-shadow: rgba(0, 0, 0, 0.2);
  --tab-separator: rgba(139, 160, 154, 0.54);
  --tab-hover-border: #6b817a;
  --tab-hover-bg: #1a201f;
  --active-tab-inset: rgba(255, 255, 255, 0.04);
  --active-tab-shadow: rgba(0, 0, 0, 0.24);
  --control-hover-border: #6a8079;
  --control-hover-bg: #1b2221;
  --note-bg: #1b2724;
  --note-warning-text: #d6ccb8;
  --button-text: #0b1715;
  --input-inset: rgba(255, 255, 255, 0.04);
  --button-shadow: rgba(0, 0, 0, 0.22);
  --button-hover-shadow: rgba(0, 0, 0, 0.26);
  --button-active-shadow: rgba(0, 0, 0, 0.18);
  --soft-shadow: rgba(0, 0, 0, 0.22);
  --secondary-shadow: rgba(0, 0, 0, 0.18);
  --secondary-hover-shadow: rgba(0, 0, 0, 0.24);
  --table-header-line: #708982;
  --table-stripe: rgba(37, 44, 40, 0.68);
  --footer-bg: rgba(28, 35, 32, 0.9);
  --logo-card-bg: #151b1a;
  --reference-border: #7c8581;
  --reference-bg: #1b1e1d;
  --reference-label-bg: #d6d0c3;
  --reference-label-text: #141817;
  --reference-text: #e5ded2;
  --reference-hover-bg: #282d2b;
  --reference-hover-text: #fff9ed;
  --reference-separator: #626b67;
  --reference-shadow: rgba(0, 0, 0, 0.24);
}

* {
  box-sizing: border-box;
}

html {
  color-scheme: light;
}

body {
  margin: 0;
  min-width: 320px;
  background: var(--page);
  color: var(--ink);
  font-size: 17px;
  font-family:
    Inter, ui-sans-serif, system-ui, -apple-system, BlinkMacSystemFont, "Segoe UI",
    sans-serif;
  line-height: 1.56;
  text-rendering: optimizeLegibility;
}

body.modal-open {
  overflow: hidden;
}

body.uds-screen-open .site-header,
body.uds-screen-open > main,
body.uds-screen-open footer {
  display: none;
}

.environment-banner {
  padding: 10px 16px;
  background: linear-gradient(90deg, var(--stage), var(--banner-end));
  color: var(--banner-text);
}

.utility-bar-content {
  display: flex;
  flex-wrap: wrap;
  gap: 18px;
  align-items: center;
  justify-content: space-between;
  width: min(1180px, calc(100% - 32px));
  margin: 0 auto;
}

.utility-brand {
  display: flex;
  flex-wrap: wrap;
  gap: 8px 14px;
  align-items: baseline;
}

.utility-brand strong {
  color: var(--banner-text);
  font-size: 1.02rem;
  font-weight: 900;
  letter-spacing: 0.01em;
}

.utility-brand span {
  color: color-mix(in srgb, var(--banner-text) 78%, transparent);
  font-size: 0.92rem;
  font-weight: 700;
}

.utility-actions {
  display: flex;
  flex-wrap: wrap;
  gap: 10px;
  align-items: center;
  justify-content: flex-end;
}

a {
  color: var(--accent-dark);
}

a:hover {
  color: var(--warning);
}

button,
input,
select {
  font: inherit;
}

button:focus-visible,
input:focus-visible,
select:focus-visible,
a:focus-visible {
  outline: 3px solid var(--focus);
  outline-offset: 3px;
}

.site-header {
  width: min(1180px, calc(100% - 32px));
  margin: 0 auto;
  padding: 28px 0 0;
}

.theme-toggle {
  display: inline-flex;
  flex: 0 0 auto;
  gap: 8px;
  align-items: center;
  justify-content: center;
  width: 158px;
  min-height: 38px;
  padding: 0 10px;
  border: 1.5px solid rgba(255, 255, 255, 0.86);
  border-radius: 9px;
  background: #f8fbfa;
  color: #24484a;
  box-shadow:
    inset 0 0 0 1px rgba(40, 112, 106, 0.1),
    0 5px 14px rgba(11, 24, 26, 0.16);
  font-size: 0.88rem;
  font-weight: 900;
  letter-spacing: 0.01em;
  white-space: nowrap;
}

.reference-control-group {
  display: inline-flex;
  align-items: stretch;
  min-height: 38px;
  overflow: hidden;
  border: 1.5px solid var(--reference-border);
  border-radius: 9px;
  background: var(--reference-bg);
  box-shadow:
    inset 0 0 0 1px rgba(255, 255, 255, 0.38),
    0 5px 14px var(--reference-shadow);
}

.reference-control-label {
  display: inline-flex;
  align-items: center;
  padding: 0 12px;
  border-right: 1.5px solid var(--reference-border);
  background: var(--reference-label-bg);
  color: var(--reference-label-text);
  font-size: 0.76rem;
  font-weight: 950;
  letter-spacing: 0.08em;
  text-transform: uppercase;
  white-space: nowrap;
}

.topbar-reference-button {
  display: inline-flex;
  flex: 0 0 62px;
  align-items: center;
  justify-content: center;
  box-sizing: border-box;
  width: 62px;
  position: relative;
  min-height: 38px;
  border: 0;
  border-radius: 0;
  padding: 0 16px;
  background: transparent;
  color: var(--reference-text);
  box-shadow: none;
  font-family: inherit;
  font-size: 0.88rem;
  font-weight: 900;
  line-height: 1;
  text-align: center;
  text-decoration: none;
  cursor: pointer;
  appearance: none;
}

.topbar-reference-button:visited {
  color: var(--reference-text);
}

.topbar-reference-button:hover {
  background: var(--reference-hover-bg);
  color: var(--reference-hover-text);
  box-shadow: none;
  transform: none;
}

.topbar-reference-button + .topbar-reference-button {
  border-left: 1.5px solid var(--reference-separator);
}

.theme-toggle-track {
  position: relative;
  width: 37px;
  height: 21px;
  flex: 0 0 37px;
  border: 1.5px solid rgba(40, 112, 106, 0.42);
  border-radius: 999px;
  background: #dfeeea;
}

.theme-toggle-thumb {
  position: absolute;
  top: 4px;
  left: 4px;
  width: 12px;
  height: 12px;
  border-radius: 999px;
  background: var(--stage);
  transition: transform 160ms ease;
}

:root[data-theme="dark"] .theme-toggle-thumb {
  transform: translateX(17px);
}

:root[data-theme="dark"] .theme-toggle {
  border-color: rgba(168, 196, 189, 0.58);
  background: #111b1c;
  color: #e7f0ed;
  box-shadow:
    inset 0 0 0 1px rgba(120, 170, 163, 0.13),
    0 5px 14px rgba(0, 0, 0, 0.2);
}

:root[data-theme="dark"] .theme-toggle-track {
  border-color: rgba(120, 170, 163, 0.5);
  background: #1d2a29;
}

:root[data-theme="dark"] .theme-toggle-thumb {
  background: #78aaa3;
}

.intro-layout {
  --warning-right-inset: 40px;
  display: grid;
  grid-template-columns: minmax(0, 780px) minmax(220px, 1fr);
  column-gap: 0;
  row-gap: 24px;
  align-items: center;
  margin: 0 0 24px;
}

.hero-copy-stack {
  display: grid;
  gap: 26px;
}

.header-copy {
  max-width: 780px;
}

.brand-logo-card {
  align-self: end;
  justify-self: center;
  width: clamp(194px, 19.8vw, 264px);
  padding: 12px;
  border: 1.5px solid var(--line);
  border-radius: 14px;
  background: var(--logo-card-bg);
  box-shadow: var(--shadow-soft);
  transform: translate(calc(var(--warning-right-inset) / -2), -15%) scale(1.15);
  transform-origin: top right;
}

.brand-logo-card img {
  display: block;
  width: 100%;
  height: auto;
  border-radius: 8px;
  transition: filter 0.3s ease, opacity 0.3s ease;
}

:root[data-theme="dark"] .brand-logo-card img {
  filter: brightness(0.72) contrast(1.02) saturate(0.88);
  opacity: 0.88;
}

:root[data-theme="dark"] .brand-logo-card img:hover {
  filter: brightness(1) contrast(1) saturate(1);
  opacity: 1;
}

.eyebrow {
  margin: 0 0 8px;
  color: var(--eyebrow);
  font-size: 0.86rem;
  font-weight: 800;
  letter-spacing: 0;
  text-transform: uppercase;
}

h1,
h2,
h3,
p {
  overflow-wrap: anywhere;
}

h1 {
  max-width: 780px;
  margin: 0;
  font-size: 2.65rem;
  line-height: 1.05;
  letter-spacing: 0;
}

h2 {
  margin: 0;
  font-size: 1.45rem;
  line-height: 1.2;
  letter-spacing: 0;
}

h3 {
  margin: 0;
  font-size: 1.06rem;
  line-height: 1.3;
  letter-spacing: 0;
}

.header-copy p:not(.eyebrow) {
  max-width: 780px;
  margin: 16px 0 0;
  color: var(--muted);
  font-size: 1.12rem;
  font-weight: 650;
}

main {
  width: min(1180px, calc(100% - 32px));
  margin: 0 auto;
}

.safety-banner {
  display: grid;
  grid-template-columns: minmax(0, 1fr);
  gap: 0;
  justify-self: start;
  align-items: center;
  width: calc(100% - var(--warning-right-inset));
  margin: 0;
  padding: 12px 22px 17px;
  border: 1.5px solid var(--warning-border);
  border-radius: 10px;
  background: var(--warning-soft);
  box-shadow: var(--shadow-soft);
}

.safety-banner strong {
  display: block;
  margin-bottom: 6px;
  color: var(--danger);
  font-size: 1.12rem;
}

.safety-banner p {
  margin: 0;
  color: var(--warning-body);
  font-size: calc(1rem - 1.333px);
  font-weight: 650;
}

.safety-banner p + p {
  margin-top: 8px;
}

.calculator-tabs {
  display: grid;
  grid-template-columns: repeat(5, minmax(0, 1fr));
  width: 100%;
  margin: 26px 0;
  padding: 6px;
  border: 1.5px solid var(--tabs-border);
  border-radius: 10px;
  background: var(--tabs-bg);
  box-shadow: 0 8px 22px var(--tabs-shadow);
}

.calculator-tab {
  position: relative;
  display: grid;
  gap: 3px;
  align-content: center;
  justify-items: center;
  min-height: 58px;
  border: 1.5px solid transparent;
  border-radius: 7px;
  padding: 10px 20px;
  background: transparent;
  color: var(--ink);
  cursor: pointer;
  text-align: center;
  box-shadow: none;
  transition:
    background-color 160ms ease,
    border-color 160ms ease,
    box-shadow 160ms ease,
    color 160ms ease,
    transform 120ms ease;
}

.calculator-tab:not(:first-child)::before {
  position: absolute;
  top: 8px;
  bottom: 8px;
  left: -1px;
  width: 2px;
  background: var(--tab-separator);
  content: "";
}

.calculator-tab.is-active::before,
.calculator-tab.is-active + .calculator-tab::before {
  display: none;
}

.calculator-tab span {
  width: 100%;
  font-size: 1rem;
  font-weight: 850;
  text-align: center;
}

.calculator-tab small {
  width: 100%;
  color: var(--muted);
  font-size: 0.86rem;
  font-weight: 650;
  text-align: center;
}

.calculator-tab.is-active {
  border-color: var(--accent);
  background: var(--accent-soft);
  color: var(--accent-dark);
  box-shadow:
    inset 0 1px 0 var(--active-tab-inset),
    0 6px 16px var(--active-tab-shadow);
}

.calculator-tab:hover {
  border-color: var(--tab-hover-border);
  background: var(--tab-hover-bg);
  box-shadow: none;
}

.calculator-tab.is-active:hover {
  background: var(--accent-soft);
}

.calculator-tab:active {
  box-shadow: none;
  transform: translateY(0);
}

.calculator-layout,
.methadone-layout,
.buprenorphine-layout,
.benzo-layout {
  display: grid;
  grid-template-columns: minmax(0, 1.05fr) minmax(320px, 0.95fr);
  gap: 24px;
  align-items: start;
  margin: 24px 0;
}

.calculator-panel,
.result-panel,
.reference-section {
  min-width: 0;
  border: 1.5px solid var(--line);
  border-radius: 10px;
  background: var(--surface);
  box-shadow: var(--shadow);
}

.calculator-panel,
.result-panel {
  padding: 26px;
}

@media (min-width: 851px) {
  #mainCalculatorSection > .result-panel,
  .methadone-layout > .result-panel {
    position: sticky;
    top: 18px;
  }
}

.compact-section {
  margin: 24px 0;
  border-top: 2px solid var(--line);
  border-bottom: 2px solid var(--line);
}

.compact-section > summary {
  display: flex;
  gap: 18px;
  align-items: center;
  justify-content: space-between;
  padding: 18px 0;
  cursor: pointer;
  list-style: none;
}

.compact-section > summary::-webkit-details-marker {
  display: none;
}

.compact-title {
  display: grid;
  gap: 5px;
}

.compact-title .eyebrow {
  margin: 0;
}

.compact-title strong {
  color: var(--ink);
  font-size: 1.28rem;
  line-height: 1.2;
}

.compact-title span:last-child {
  color: var(--muted);
  font-size: 0.95rem;
}

.summary-action {
  flex: 0 0 auto;
  border: 1.5px solid var(--line);
  border-radius: 8px;
  padding: 8px 12px;
  background: var(--surface-soft);
  color: var(--ink);
  font-weight: 850;
}

.summary-action::before {
  content: "Show";
}

.compact-section[open] .summary-action::before {
  content: "Hide";
}

.compact-section-body.methadone-layout,
.compact-section-body.buprenorphine-layout,
.compact-section-body.reference-section {
  margin: 0 0 24px;
}

.organ-context {
  margin: 24px 0;
  border: 1.5px solid var(--line);
  border-radius: 8px;
  background: var(--surface-soft);
}

.organ-context > summary {
  display: flex;
  gap: 18px;
  align-items: center;
  justify-content: space-between;
  padding: 16px;
  cursor: pointer;
  list-style: none;
}

.organ-context > summary::-webkit-details-marker {
  display: none;
}

.organ-context > summary strong {
  display: block;
  font-size: 1.05rem;
}

.organ-context[open] .summary-action::before {
  content: "Hide";
}

.organ-context .context-grid {
  padding: 0 16px 16px;
}

.specialty-section {
  margin: 24px 0;
}

.specialty-tool-panel {
  margin: 0;
}

.section-heading,
.subsection-heading {
  margin-bottom: 20px;
  padding-bottom: 14px;
  border-bottom: 2px solid var(--line);
}

.field-grid {
  display: grid;
  gap: 18px;
}

.compact-grid {
  grid-template-columns: repeat(2, minmax(0, 1fr));
  align-items: start;
}

.compact-grid > label {
  align-content: start;
}

.field-stack {
  display: grid;
  gap: 8px;
  align-content: start;
}

#targetField {
  grid-template-columns: minmax(0, 1fr);
}

.target-field {
  margin-top: 24px;
  padding-top: 20px;
  border-top: 2px solid var(--line);
}

.field-stack > label {
  align-content: start;
}

.conversion-field-title {
  display: block;
  color: var(--ink);
  font-size: 1.24rem;
  font-weight: 900;
  letter-spacing: -0.01em;
  line-height: 1.15;
}

.top-grid-note {
  display: block;
  margin-top: 0;
}

label,
.slider-header label {
  display: grid;
  gap: 8px;
  color: var(--ink);
  font-size: 1.01rem;
  font-weight: 800;
}

.field-hint {
  color: var(--muted);
  font-size: 0.94rem;
  font-weight: 700;
}

.is-hidden {
  display: none !important;
}

select,
input[type="number"] {
  width: 100%;
  min-height: 50px;
  border: 1.5px solid var(--line);
  border-radius: 6px;
  background: var(--surface);
  color: var(--ink);
  padding: 11px 13px;
  font-size: 1rem;
  box-shadow: inset 0 1px 0 var(--input-inset);
  transition:
    background-color 160ms ease,
    border-color 160ms ease,
    box-shadow 160ms ease;
}

select:hover,
input[type="number"]:hover {
  border-color: var(--control-hover-border);
  background: var(--control-hover-bg);
}

select {
  cursor: pointer;
}

.subsection {
  margin-top: 24px;
  padding-top: 20px;
  border-top: 2px solid var(--line);
}

#calculationMode + .subsection {
  margin-top: 0;
  padding-top: 0;
  border-top: 0;
}

.subsection-header {
  display: flex;
  gap: 16px;
  align-items: center;
  justify-content: space-between;
}

.regimen-entries {
  display: grid;
  gap: 16px;
  margin-top: 18px;
}

.regimen-entry {
  padding: 18px;
  border: 1.5px solid var(--line);
  border-radius: 8px;
  background: var(--surface);
}

.entry-head {
  display: flex;
  gap: 16px;
  align-items: flex-start;
  justify-content: space-between;
  margin-bottom: 14px;
}

.entry-head h3 {
  margin-top: 0;
  color: var(--accent-dark);
  font-size: 1.28rem;
  font-weight: 900;
  line-height: 1.15;
}

.entry-remove-button {
  min-height: 38px;
  padding: 8px 12px;
}

.regimen-entry-grid {
  display: grid;
  grid-template-columns: repeat(2, minmax(0, 1fr));
  gap: 14px;
}

.regimen-entry-grid > label:first-child {
  grid-column: 1 / -1;
}

.entry-summary {
  margin: 14px 0 0;
  color: var(--muted);
  font-size: 0.98rem;
  font-weight: 650;
}

.slider-group {
  display: grid;
  gap: 12px;
}

.slider-header {
  display: flex;
  gap: 16px;
  align-items: end;
  justify-content: space-between;
}

.percent-input {
  display: grid;
  grid-template-columns: minmax(72px, 92px) auto;
  gap: 8px;
  align-items: center;
}

.percent-input input {
  text-align: right;
}

input[type="range"] {
  width: 100%;
  accent-color: var(--accent);
}

.range-labels {
  display: flex;
  justify-content: space-between;
  color: var(--muted);
  font-size: 0.9rem;
  font-weight: 650;
}

.quick-actions {
  display: flex;
  flex-wrap: wrap;
  gap: 10px;
  margin-top: 14px;
}

.tag-button {
  min-height: 38px;
  border: 1.5px solid var(--line);
  border-radius: 8px;
  background: var(--surface);
  color: var(--ink);
  cursor: pointer;
  font-weight: 750;
  padding: 8px 12px;
  transition:
    background-color 160ms ease,
    border-color 160ms ease,
    box-shadow 160ms ease,
    transform 120ms ease;
}

.tag-button:hover {
  border-color: var(--control-hover-border);
  background: var(--surface-soft);
  box-shadow: 0 6px 14px var(--soft-shadow);
  transform: translateY(-1px);
}

.tag-button:active {
  box-shadow: none;
  transform: translateY(0);
}

.basis-note,
.reference-copy {
  margin: 18px 0 0;
  color: var(--muted);
  font-size: 0.99rem;
  font-weight: 650;
}

.context-grid,
.advisory-grid {
  display: grid;
  grid-template-columns: 1fr;
  gap: 18px;
  margin-top: 24px;
}

.context-card,
.advisory-card {
  padding: 20px;
  border: 1.5px solid var(--line);
  border-radius: 8px;
  background: var(--surface-soft);
}

.context-card h3,
.advisory-card h3 {
  font-size: 1.12rem;
}

.context-summary,
.advisory-card p {
  margin: 14px 0 0;
  color: var(--muted);
}

.note-box {
  padding: 13px 15px;
  border-left: 4px solid var(--accent);
  border-radius: 6px;
  background: var(--note-bg);
}

.note-box-accent {
  border-left-color: var(--warning);
  background: var(--warning-soft);
  color: var(--note-warning-text);
}

.note-box h4 {
  margin: 0 0 8px;
  color: var(--ink);
  font-size: 1.03rem;
  font-weight: 850;
}

.note-box p {
  margin: 0;
  color: var(--ink);
  font-size: 0.93rem;
  font-weight: 650;
  line-height: 1.45;
}

.note-box p + p {
  margin-top: 8px;
}

.button-row {
  display: flex;
  flex-wrap: wrap;
  gap: 12px;
  margin-top: 22px;
}

button {
  min-height: 46px;
  border: 0;
  border-radius: 8px;
  background: var(--accent);
  color: var(--button-text);
  cursor: pointer;
  font-size: 1rem;
  font-weight: 800;
  padding: 10px 16px;
  box-shadow: 0 8px 18px var(--button-shadow);
  transition:
    background-color 160ms ease,
    border-color 160ms ease,
    box-shadow 160ms ease,
    color 160ms ease,
    transform 120ms ease;
}

button:hover {
  background: var(--accent-dark);
  box-shadow: 0 10px 22px var(--button-hover-shadow);
  transform: translateY(-1px);
}

button:active {
  box-shadow: 0 4px 12px var(--button-active-shadow);
  transform: translateY(0);
}

.secondary-button {
  border: 1.5px solid var(--line);
  background: var(--surface);
  color: var(--ink);
  box-shadow: 0 6px 16px var(--secondary-shadow);
}

.secondary-button:hover {
  border-color: var(--control-hover-border);
  background: var(--surface-soft);
  box-shadow: 0 8px 20px var(--secondary-hover-shadow);
}

.theme-toggle:hover {
  border-color: rgba(255, 255, 255, 0.96);
  background: #ffffff;
  color: #183638;
  box-shadow:
    inset 0 0 0 1px rgba(40, 112, 106, 0.14),
    0 6px 15px rgba(11, 24, 26, 0.2);
  transform: none;
}

:root[data-theme="dark"] .theme-toggle:hover {
  border-color: rgba(168, 196, 189, 0.74);
  background: #172425;
  color: #f2fbf8;
  box-shadow:
    inset 0 0 0 1px rgba(120, 170, 163, 0.18),
    0 6px 15px rgba(0, 0, 0, 0.24);
}

.theme-toggle:active {
  box-shadow:
    inset 0 0 0 1px rgba(255, 255, 255, 0.16),
    0 3px 10px rgba(11, 24, 26, 0.1);
  transform: none;
}

.secondary-button:disabled {
  cursor: not-allowed;
  opacity: 0.55;
  box-shadow: none;
  transform: none;
}

.dose-result {
  display: flex;
  gap: 10px;
  align-items: baseline;
  min-height: 98px;
  margin: 8px 0 10px;
  padding: 8px 0;
  color: var(--accent-dark);
}

#finalDose,
#methadoneConservativeMmeDose,
#methadoneFinalDose,
#benzoFinalDose {
  font-size: 4.35rem;
  font-weight: 850;
  line-height: 1;
}

#finalUnit,
#methadoneConservativeMmeUnit,
#methadoneFinalUnit,
#benzoFinalUnit {
  font-size: 1.5rem;
  font-weight: 800;
}

.secondary-dose-card {
  margin: 18px 0 24px;
  padding: 18px;
  border: 1.5px solid var(--line);
  border-left: 5px solid var(--accent);
  border-radius: 8px;
  background: var(--note-bg);
}

.secondary-dose-result {
  margin: 6px 0;
}

.secondary-dose-card p {
  margin: 0;
  color: var(--muted);
  font-weight: 700;
}

.calculation-steps {
  display: grid;
  gap: 0;
  margin: 0;
}

.calculation-steps div {
  display: grid;
  grid-template-columns: minmax(180px, 0.9fr) minmax(0, 1.1fr);
  gap: 16px;
  align-items: center;
  min-height: 56px;
  padding: 10px 0;
  border-top: 2px solid var(--line);
}

.calculation-steps .wrap-step {
  grid-template-columns: 1fr;
  align-items: start;
  gap: 4px;
}

.calculation-steps div:last-child {
  border-bottom: 2px solid var(--line);
}

dt {
  color: var(--muted);
  font-weight: 800;
}

dd {
  margin: 0;
  color: var(--ink);
  font-weight: 850;
  font-size: 1.02rem;
  text-align: right;
  overflow-wrap: anywhere;
}

.calculation-steps .wrap-step dd {
  text-align: left;
}

.clinical-notes {
  margin-top: 22px;
}

.clinical-notes ul {
  margin: 0;
  padding-left: 20px;
}

.clinical-notes li {
  margin: 8px 0;
  line-height: 1.58;
}

.schedule-summary {
  display: grid;
  gap: 12px;
  margin-bottom: 20px;
}

.schedule-summary div {
  display: grid;
  gap: 4px;
  border-top: 2px solid var(--line);
  padding-top: 12px;
}

.schedule-summary div:first-child {
  border-top: 0;
  padding-top: 0;
}

.schedule-summary div:last-child {
  border-bottom: 2px solid var(--line);
  padding-bottom: 12px;
}

.summary-label {
  color: var(--muted);
  font-size: 0.88rem;
  font-weight: 800;
  letter-spacing: 0;
  text-transform: uppercase;
}

.schedule-table-wrap,
.regimen-table-wrap {
  margin-top: 8px;
}

.schedule-table {
  min-width: 560px;
}

.regimen-table {
  min-width: 620px;
}

.result-panel .regimen-table,
.result-panel .schedule-table {
  min-width: 0;
  table-layout: fixed;
}

.result-panel .regimen-table th,
.result-panel .regimen-table td,
.result-panel .schedule-table th,
.result-panel .schedule-table td {
  padding: 12px 10px;
  overflow-wrap: break-word;
  word-break: normal;
}

.result-panel .regimen-table th:last-child,
.result-panel .regimen-table td:last-child,
.result-panel .schedule-table th:last-child,
.result-panel .schedule-table td:last-child {
  text-align: left;
}

.result-panel .regimen-table th:nth-child(1),
.result-panel .regimen-table td:nth-child(1) {
  width: 36%;
}

.result-panel .regimen-table th:nth-child(2),
.result-panel .regimen-table td:nth-child(2) {
  width: 29%;
}

.result-panel .regimen-table th:nth-child(3),
.result-panel .regimen-table td:nth-child(3) {
  width: 35%;
}

.result-panel .schedule-table th:nth-child(1),
.result-panel .schedule-table td:nth-child(1) {
  width: 11%;
}

.result-panel .schedule-table th:nth-child(2),
.result-panel .schedule-table td:nth-child(2) {
  width: 35%;
}

.result-panel .schedule-table th:nth-child(3),
.result-panel .schedule-table td:nth-child(3) {
  width: 54%;
}

.output-stack {
  display: grid;
  gap: 2px;
}

.output-detail {
  color: var(--muted);
  font-size: 0.9rem;
  font-weight: 650;
}

.source-table {
  min-width: 720px;
}

.pharmacokinetics-table {
  min-width: 1060px;
  table-layout: fixed;
}

.pk-reference-block {
  display: grid;
  gap: 14px;
}

.pk-interactive-layout {
  display: grid;
  grid-template-columns: minmax(0, 1fr) minmax(430px, 0.55fr);
  gap: 18px;
  align-items: start;
}

.pk-graph-grid {
  display: grid;
  grid-template-columns: repeat(auto-fit, minmax(230px, 1fr));
  gap: 14px;
}

.pk-graph-card {
  display: grid;
  gap: 10px;
  min-width: 0;
  min-height: auto;
  border: 1.5px solid var(--line);
  border-radius: 10px;
  padding: 14px;
  background: var(--surface-soft);
  color: var(--ink);
  text-align: left;
  box-shadow: none;
}

.pk-graph-card:hover {
  border-color: color-mix(in srgb, var(--accent) 48%, var(--line));
  background: color-mix(in srgb, var(--surface-soft) 74%, var(--accent-soft));
  box-shadow: none;
  transform: none;
}

.pk-graph-card.is-selected {
  border-color: var(--accent);
  background: var(--surface);
  box-shadow:
    inset 0 0 0 1px color-mix(in srgb, var(--accent) 42%, transparent),
    0 10px 24px var(--secondary-shadow);
}

.pk-graph-card-head {
  display: grid;
  gap: 2px;
}

.pk-graph-card-head strong {
  color: var(--ink);
  font-size: 1rem;
  font-weight: 850;
}

.pk-graph-card-head span,
.pk-graph-meta {
  color: var(--muted);
  font-size: 0.82rem;
  font-weight: 750;
}

.pk-profile-svg {
  width: 100%;
  min-height: 96px;
  overflow: visible;
}

.pk-axis {
  stroke: var(--table-header-line);
  stroke-width: 1.5;
}

.pk-marker {
  stroke: color-mix(in srgb, var(--accent) 42%, transparent);
  stroke-dasharray: 4 4;
  stroke-width: 1.4;
}

.pk-marker-offset {
  stroke: color-mix(in srgb, var(--warning) 48%, transparent);
}

.pk-profile-line {
  fill: none;
  stroke: var(--accent);
  stroke-linecap: round;
  stroke-linejoin: round;
  stroke-width: 4;
}

.pk-axis-label {
  fill: var(--muted);
  font-size: 11px;
  font-weight: 800;
}

.pk-graph-meta {
  display: flex;
  flex-wrap: wrap;
  gap: 6px 12px;
  justify-content: space-between;
}

.pk-selected-detail {
  position: sticky;
  top: 12px;
  z-index: 2;
  display: grid;
  gap: 16px;
  max-height: calc(90vh - 190px);
  overflow: auto;
  border: 1.5px solid color-mix(in srgb, var(--accent) 34%, var(--line));
  border-radius: 10px;
  padding: 18px;
  background: var(--surface);
  box-shadow: 0 10px 24px var(--secondary-shadow);
}

.pk-selected-detail-head {
  display: grid;
  gap: 4px;
}

.pk-selected-detail-head h4,
.pk-selected-detail-head .eyebrow {
  margin: 0;
}

.pk-selected-detail-head h4 {
  color: var(--ink);
  font-size: 1.25rem;
}

.pk-selected-detail-head .pk-selected-route {
  color: var(--muted);
  font-weight: 750;
}

.pk-selected-detail-head p {
  margin: 6px 0 0;
  color: var(--muted);
  font-size: 0.92rem;
  font-weight: 700;
  line-height: 1.45;
}

.pk-selected-detail-grid {
  display: grid;
  grid-template-columns: 1fr;
  gap: 14px 18px;
}

.pk-selected-detail-grid div {
  display: grid;
  gap: 5px;
}

.pk-selected-detail-grid dt {
  color: var(--accent-dark);
  font-size: 0.82rem;
  font-weight: 900;
  letter-spacing: 0.04em;
  text-transform: uppercase;
}

.pk-selected-detail-grid dd {
  margin: 0;
  color: var(--ink);
  font-size: 0.96rem;
  font-weight: 650;
  line-height: 1.55;
  text-align: left;
}

.is-selected-reference-row {
  background: color-mix(in srgb, var(--accent-soft) 72%, var(--surface)) !important;
}

.pk-comparison-details {
  border-top: 2px solid var(--line);
  border-bottom: 2px solid var(--line);
}

.pk-comparison-details > summary {
  display: flex;
  gap: 18px;
  align-items: center;
  justify-content: space-between;
  padding: 16px 0;
  cursor: pointer;
  list-style: none;
}

.pk-comparison-details > summary::-webkit-details-marker {
  display: none;
}

.pk-comparison-details > summary > span:first-child {
  display: grid;
  gap: 5px;
}

.pk-comparison-details > summary strong {
  color: var(--ink);
  font-size: 1.12rem;
  line-height: 1.2;
}

.pk-comparison-details > summary span:last-child:not(.summary-action) {
  color: var(--muted);
  font-size: 0.92rem;
  font-weight: 650;
}

.pk-comparison-details[open] .summary-action::before {
  content: "Hide";
}

.pk-comparison-body {
  display: grid;
  gap: 14px;
  padding: 0 0 18px;
}

.pk-comparison-body .reference-copy {
  margin-top: 0;
}

.pharmacokinetics-table th:nth-child(1),
.pharmacokinetics-table td:nth-child(1) {
  width: 15%;
}

.pharmacokinetics-table th:nth-child(2),
.pharmacokinetics-table td:nth-child(2) {
  width: 17%;
}

.pharmacokinetics-table th:nth-child(3),
.pharmacokinetics-table td:nth-child(3) {
  width: 17%;
}

.pharmacokinetics-table th:nth-child(4),
.pharmacokinetics-table td:nth-child(4) {
  width: 20%;
}

.pharmacokinetics-table th:nth-child(5),
.pharmacokinetics-table td:nth-child(5) {
  width: 16%;
}

.pharmacokinetics-table th:nth-child(6),
.pharmacokinetics-table td:nth-child(6) {
  width: 15%;
}

.pharmacokinetics-table td,
.pharmacokinetics-table th {
  font-size: 0.92rem;
  line-height: 1.5;
  overflow-wrap: anywhere;
}

.table-subtext,
.source-link-stack {
  display: grid;
  gap: 6px;
}

.table-subtext {
  margin-top: 6px;
  color: var(--muted);
  font-size: 0.82rem;
  font-weight: 750;
}

.source-link-stack {
  font-weight: 800;
  overflow-wrap: break-word;
  word-break: normal;
}

.source-link-stack a {
  text-decoration: underline;
  text-underline-offset: 3px;
  transition: color 0.15s ease;
}

.pharmacokinetics-notes {
  padding-top: 2px;
}

.continue-action {
  color: var(--accent-dark);
  font-weight: 850;
}

.taper-action {
  color: var(--warning);
  font-weight: 850;
}

.stop-action {
  color: var(--danger);
  font-weight: 900;
}

.reference-section {
  margin: 24px 0 34px;
  padding: 24px;
}

.methadone-reference-heading {
  margin-top: 28px;
}

.table-wrap {
  overflow-x: auto;
}

table {
  width: 100%;
  min-width: 780px;
  border-collapse: collapse;
}

th,
td {
  border-bottom: 1px solid var(--line);
  padding: 15px 13px;
  text-align: left;
  vertical-align: top;
  font-size: 0.98rem;
}

th {
  background: var(--surface-soft);
  border-bottom: 2px solid var(--table-header-line);
  color: var(--ink);
  font-weight: 850;
}

tbody tr:nth-child(even) {
  background: var(--table-stripe);
}

td:last-child,
th:last-child {
  text-align: right;
}

.source-table td:last-child,
.source-table th:last-child,
.pharmacokinetics-table td:last-child,
.pharmacokinetics-table th:last-child,
.schedule-table td:last-child,
.schedule-table th:last-child {
  text-align: left;
}

footer {
  border-top: 1px solid var(--line);
  background: var(--footer-bg);
}

.footer-content {
  width: min(1180px, calc(100% - 32px));
  margin: 0 auto;
  padding: 11px 0;
  color: var(--muted);
  font-size: 0.9rem;
  font-weight: 650;
}

.reference-modal {
  position: fixed;
  inset: 0;
  z-index: 1000;
  display: grid;
  align-items: center;
  justify-items: center;
  padding: 14px;
  background: rgba(6, 18, 16, 0.58);
}

.reference-dialog {
  width: min(1480px, 100%);
  max-height: min(90vh, 900px);
  overflow: auto;
  border: 1.5px solid var(--line);
  border-radius: 12px;
  background: var(--surface);
  color: var(--ink);
  box-shadow: 0 24px 72px rgba(0, 0, 0, 0.28);
}

.reference-modal-header {
  display: flex;
  gap: 18px;
  align-items: start;
  justify-content: space-between;
  padding: 22px 24px 18px;
  border-bottom: 2px solid var(--line);
  background: var(--surface-soft);
}

.reference-modal-header h2,
.reference-modal-header p {
  margin: 0;
}

.reference-modal-header > div {
  display: grid;
  gap: 6px;
}

.reference-modal-header .eyebrow {
  margin: 0;
}

.reference-modal-header p:not(.eyebrow) {
  color: var(--muted);
  font-weight: 700;
}

.modal-close-button {
  flex: 0 0 auto;
}

.reference-modal-body {
  display: grid;
  gap: 28px;
  padding: 24px;
}

.uds-screen {
  padding: 22px 16px 44px;
  background: var(--page);
}

.uds-screen-shell {
  width: min(1462px, 85%);
  margin: 0 auto;
  border: 1.5px solid var(--line);
  border-radius: 12px;
  background: var(--surface);
  color: var(--ink);
  box-shadow: 0 16px 42px var(--secondary-shadow);
}

@media (max-width: 1040px) {
  .uds-screen-shell {
    width: 100%;
  }
}

.uds-screen-header {
  display: grid;
  grid-template-columns: auto minmax(0, 1fr) auto;
  gap: 18px;
  align-items: start;
  padding: 22px 24px 18px;
  border-bottom: 2px solid var(--line);
  background: var(--surface-soft);
}

.uds-screen-header h2,
.uds-screen-header p {
  margin: 0;
}

.uds-screen-header > div {
  display: grid;
  gap: 6px;
}

.uds-screen-header .eyebrow {
  margin: 0;
}

.uds-screen-header p:not(.eyebrow) {
  color: var(--muted);
  font-weight: 700;
}

.uds-back-button {
  min-width: 92px;
  border-color: var(--reference-border);
  background: var(--reference-label-bg);
  color: var(--reference-label-text);
  font-weight: 900;
  box-shadow: 0 8px 18px var(--reference-shadow);
}

.uds-back-button:hover {
  border-color: var(--reference-separator);
  background: var(--reference-hover-bg);
  color: var(--reference-hover-text);
}

.uds-value-button {
  align-self: start;
  border-color: var(--reference-border);
  background: var(--reference-bg);
  color: var(--reference-text);
  font-size: 0.86rem;
  font-weight: 900;
  box-shadow: 0 7px 16px var(--reference-shadow);
  white-space: nowrap;
}

.uds-value-button:hover {
  border-color: var(--reference-separator);
  background: var(--reference-hover-bg);
  color: var(--reference-hover-text);
}

.uds-value-dialog {
  width: min(980px, 100%);
}

.uds-value-body {
  gap: 18px;
}

.uds-value-summary-card,
.uds-value-impact,
.uds-value-grid article {
  padding: 16px;
  border: 2px solid var(--line);
  border-radius: 11px;
  background: var(--surface-warm);
}

.uds-value-summary-card h3,
.uds-value-impact h3,
.uds-value-grid h3,
.uds-value-summary-card p,
.uds-value-impact p,
.uds-value-grid p {
  margin: 0;
}

.uds-value-summary-card h3,
.uds-value-impact h3,
.uds-value-grid h3 {
  color: var(--eyebrow);
  font-size: 0.86rem;
  font-weight: 950;
  letter-spacing: 0.08em;
  text-transform: uppercase;
}

.uds-value-summary-card p,
.uds-value-impact p,
.uds-value-grid p {
  margin-top: 8px;
  color: var(--ink);
  font-weight: 700;
  line-height: 1.48;
}

.uds-value-grid {
  display: grid;
  grid-template-columns: repeat(2, minmax(0, 1fr));
  gap: 14px;
}

.uds-screen-body {
  display: grid;
  gap: 28px;
  padding: 24px;
}

@media (max-width: 960px) {
  .pk-interactive-layout,
  .compact-grid,
  .regimen-entry-grid {
    grid-template-columns: 1fr;
  }

  .regimen-entry-grid > label:first-child {
    grid-column: auto;
  }
}

@media (max-width: 850px) {
  .intro-layout,
  .safety-banner,
  .calculator-layout,
  .methadone-layout,
  .buprenorphine-layout,
  .benzo-layout {
    grid-template-columns: 1fr;
  }

  .calculator-tabs {
    grid-template-columns: repeat(2, minmax(0, 1fr));
    width: 100%;
  }

  .calculator-tab::before {
    display: none;
  }

  .site-header {
    padding-top: 22px;
  }

  .brand-logo-card {
    align-self: auto;
    justify-self: center;
    width: clamp(122px, 34vw, 168px);
    padding: 8px;
    transform: none;
  }

  h1 {
    font-size: 2.2rem;
  }
}

@media (max-width: 560px) {
  .site-header,
  main,
  .footer-content {
    width: min(100% - 22px, 1180px);
  }

  h1 {
    font-size: 1.9rem;
  }

  .calculator-tabs {
    grid-template-columns: 1fr;
  }

  .calculator-panel,
  .result-panel,
  .reference-section,
  .safety-banner,
  .context-card,
  .advisory-card,
  .regimen-entry {
    padding: 16px;
  }

  .compact-section > summary,
  .organ-context > summary,
  .subsection-header,
  .entry-head,
  .slider-header {
    align-items: stretch;
    display: grid;
  }

  .button-row {
    display: grid;
  }

  button,
  .tag-button {
    width: 100%;
  }

  .theme-toggle {
    width: auto;
  }

  .reference-control-group {
    width: 100%;
  }

  .reference-control-label {
    flex: 1 1 auto;
  }

  .topbar-reference-button {
    flex: 1 1 0;
    width: auto;
  }

  .reference-modal {
    padding: 12px;
  }

  .reference-modal-header,
  .reference-modal-body,
  .uds-screen-header,
  .uds-screen-body {
    padding-right: 18px;
    padding-left: 18px;
  }

  .reference-modal-header,
  .uds-screen-header {
    display: grid;
  }

  .uds-screen-header {
    grid-template-columns: 1fr;
  }

  .uds-back-button {
    width: max-content;
  }

  .uds-value-button {
    width: max-content;
  }

  .uds-value-grid {
    grid-template-columns: 1fr;
  }

  .pk-selected-detail-grid {
    grid-template-columns: 1fr;
  }

  #finalDose,
  #methadoneConservativeMmeDose,
  #methadoneFinalDose,
  #benzoFinalDose {
    font-size: 3.1rem;
  }

  .calculation-steps div {
    display: grid;
    gap: 4px;
    justify-content: stretch;
    padding: 10px 0;
  }

  dd {
    text-align: left;
  }
}